Impact of a Virtual Reality-Based Simulation on Empathy and Attitudes Toward Schizophrenia

Virtual Reality (VR) has been identified as one of the most promising resources for developing empathy towards stigmatized groups as it allows individuals to experience a situation close to reality from another person’s perspective. This quasi-experimental study aimed to examine the impact on empathy, knowledge, and attitudes towards people with schizophrenia of a VR simulation that reproduces the experience of psychotic symptoms while performing a cognitive task compared with watching a 2D video and, thus, how these experiences could reduce stigma towards people diagnosed with schizophrenia. The sample comprised of 102 higher education health students, distributed by the experimental and control groups. The impact of the program was measured by completing multiple questionnaires on levels of empathy, attitudes, and mental health knowledge. Both methods (VR and 2D video) were, to a certain extent, effective. However, VR was more effective at eliciting attitudes and knowledge change compared to the control group. These findings suggest that not only VR but also 2D videos could be interesting strategies to enhance empathy and improve attitudes towards people with schizophrenia in higher education health students

Effect of a specific concurrent water and dry-land training over a season in young swimmers’ performance

The aims of this study were to assess over a full season: (i) the effect of a combined dry-land strength and conditioning and in-water program on the swimming performance of young swimmers; (ii) the effect of such program on the performance determinants; (iii) the effect of the training periodization designed. A longitudinal research design assessing an age-group of young swimmers over a season was carried out. Methods: Twenty-seven young swimmers (12 boys: 13.55±0.72-y; 15 girls: 13.16±0.93-y; both sexes in Tanner stages 2-3) were evaluated in three moments over 40 weeks. The 100-m freestyle performance, body mass, height, arm span (anthropometrics), stroke frequency, stroke length, swimming velocity, intracyclic swimming velocity (kinematics), stroke index, propelling efficiency (efficiency), squat jump, countermovement jump, and throw velocity (strength and conditioning) were assessed. A cluster analysis was computed to classify the swimmers. For the “talented” swimmers, the performance and all determinants, but the squat and countermovement jumps improved between the first and last evaluation moments. Both in-water and dry-land strength and conditioning features were responsible for the cluster discrimination in each one of the evaluation moments. All three clusters were also characterized by a mix of technical and strength & conditioning features. This highlights swimming performance as a holistic phenomenon (i.e. multiple determinants) where shifting occur in the interplay among the performance determinant according to the training periodization.info:eu-repo/semantics/publishedVersio

Isatina: “Bloco de Construção” Promissor no Desenvolvimento de Novos Fármacos

A isatina (ou 1H-indole-2,3-diona) é um composto heterocíclico muito cobiçado nas áreas da química medicinal e sintética devido à sua estrutura particularmente versátil no que diz respeito à possibilidade de modificação estrutural e no leque imenso de aplicações que possui. Nos últimos anos tem sido vastamente modificada de forma a provar o seu interesse como potencial fármaco. Neste artigo pretende-se mostrar o trabalho realizado por nós no âmbito do design e síntese de novas famílias de compostos do tipo oxindole, e de mostrar a sua potencial aplicação em duas doenças preocupantes da atualidade, a doença de Alzheimer e o cancro

Longitudinal modeling in sports: young swimmers' performance and biomechanics profile

The aims was to model a latent growth curve of young swimmers' performance over a season and its relationship with biomechanics, quantify the direct effect of the exogenous variables selected on performance across a season and analyze the sex effect on the performance growth. Fourteen boys (12.33±0.65 years) and 16 girls (11.15±0.55 years) were evaluated. Performance, stroke frequency, speed fluctuation, arm's propelling efficiency, active drag, active drag coefficient and power to overcome drag were collected in four different moments of the season. Latent growth curve modeling was computed to understand the longitudinal variation of performance (endogenous variables) over the season according to the biomechanics (exogenous variables). Latent growth curve modeling showed a high inter- and intra-subject variability in the performance growth. Sex had a significant effect at the baseline and during the performance growth. In each evaluation moment, different variables had a meaningful effect on performance (M1: Da, β=-0.62; M2: Da, β=-0.53; M3: ηp, β=0.59; M4: SF, β=-0.57; all P<0.001). The models' good-of-fit was 1.40≤x2/df≤3.74 (good-reasonable). Latent modeling is a comprehensive way to gather insight about young swimmers' performance over time. Different variables were the main responsible for the performance improvement. A gender gap, intra- and inter-subject variability was verified

Does d-cycloserine facilitate the effects of homework compliance on social anxiety symptom reduction?

BACKGROUND: Prior studies examining the effect of d-cycloserine (DCS) on homework compliance and outcome in cognitive-behavior therapy (CBT) have yielded mixed results. The aim of this study was to investigate whether DCS facilitates the effects of homework compliance on symptom reduction in a large-scale study for social anxiety disorder (SAD). METHODS: 169 participants with generalized SAD received DCS or pill placebo during 12-session exposure-based group CBT. Improvements in social anxiety were assessed by independent raters at each session using the Liebowitz social anxiety scale (LSAS). RESULTS: Controlling for LSAS at the previous session, and irrespective of treatment condition, greater homework compliance in the week prior related to lower LSAS at the next session. However, DCS did not moderate the effect of homework compliance and LSAS, LSAS on homework compliance, or the overall augmenting effect of DCS on homework compliance. Furthermore, LSAS levels were not predictive of homework compliance in the following week. CONCLUSION: The findings support the general benefits of homework compliance on outcome, but not a DCS-augmenting effect. The comparably small number of DCS-enhanced sessions in this study could be one reason for the failure to find a facilitating effect of DCS

A simple ESR identification methodology for electrolytic capacitors condition monitoring

Electrolytic capacitors are usually used in power electronic systems for smoothing, energy storage or filtering. They have the best overall performance for these objectives being a critical element in the design of these systems, in several applications, with different requirements. But, unfortunately, in most cases, they are the most life-limiting device. The expected life of electrolytic capacitors depends on their internal temperature and is determined by the ratio of the electrolyte solution evaporation used in their fabrication. The deterioration caused by this evaporation is reflected in electrical parameters, mainly the equivalent series resistance (ESR). As the volume of the electrolyte decreases, ESR increases and capacitance decreases. Additionally, the increase in ESR has a positive feedback effect since it leads the temperature to increase and this in turn leads to further evaporation of the electrolyte leading to the ESR increase and so forth. This paper presents a simple ESR identification methodology for electrolytic capacitors condition monitoring in view of preventive maintenance to signal the need of maintenance and or replacement. The identification methodology is based on a simple continuous-time model and some recursive prediction error methods, namely, Kalman filter, gradient and forgetting factor approaches. Simulation and experimental data acquired from a step down converter were used with these algorithms. The identification methodology is also suitable for different power converter topologies

The influence of anthropometric, kinematic and energetic variables and gender on swimming performance in youth athletes

The aim of this study was to assess the: (i) gender; (ii) performance and; (iii) gender versus performance interactions in young swimmers’ anthropometric, kinematic and energetic variables. One hundred and thirty six young swimmers (62 boys: 12.76 ± 0.72 years old at Tanner stages 1-2 by self-evaluation; and 64 girls: 11.89 ± 0.93 years old at Tanner stages 1-2 by self-evaluation) were evaluated. Performance, anthropometrics, kinematics and energetic variables were selected. There was a non-significant gender effect on performance, body mass, height, arm span, trunk transverse surface area, stroke length, speed fluctuation, swimming velocity, propulsive efficiency, stroke index and critical velocity. A significant gender effect was found for foot surface area, hand surface area and stroke frequency. A significant sports level effect was verified for all variables, except for stroke frequency, speed fluctuation and propulsive efficiency. Overall, swimmers in quartile 1 (the ones with highest sports level) had higher anthropometric dimensions, better stroke mechanics and energetics. These traits decrease consistently throughout following quartiles up to the fourth one (i.e. swimmers with the lowest sports level). There was a non-significant interaction between gender and sports level for all variables. Our main conclusions were as follows: (i) there are non-significant differences in performance, anthropometrics, kinematics and energetics between boys and girls; (ii) swimmers with best performance are taller, have higher surface areas and better stroke mechanics; (iii) there are non-significant interactions between sports level and gender for anthropometrics, kinematics and energetics

A path-flow analysis model for active drag force determinant variables in age-group swimmers

The goal of competitive swimming is to travel the event distance as fast as possible. The identification of the parameters that predict swimming performances is one of the main aims of the swimming “science” community. Indeed, it is consensual that biomechanical and energetic variables are determinant for enhance performance (Barbosa et al, 2010)

Hydrodynamic profile of young swimmers: changes over a competitive season

The aim of this study was to analyze the changes in the hydrodynamic profile of young swimmers over a competitive season and to compare the variations according to a well-designed training periodization. Twenty-five swimmers (13 boys and 12 girls) were evaluated in (a) October (M1); (b) March (M2); and (c) June (M3). Inertial and anthropometrical measures included body mass, swimmer’s added water mass, height, and trunk transverse surface area. Swimming efficiency was estimated by the speed fluctuation, stroke index, and approximate entropy. Active drag was estimated with the velocity perturbation method and the passive drag with the gliding decay method. Hydrodynamic dimen- sionless numbers (Froude and Reynolds numbers) and hull velocity (i.e., speed at Froude number = 0.42) were also calculated. No variable presented a significant gender effect. Anthropometrics and inertial parameters plus dimensionless numbers increased over time. Swimming efficiency improved between M1 and M3. There was a trend for both passive and active drag increase from M1 to M2, but being lower at M3 than at M1. Intra-individual changes between evaluation moments suggest high between- and within-subject variations. Therefore, hydrodynamic changes over a season occur in a non-linear fashion way, where the interplay between growth and training periodization explain the unique path flow selected by each young swimmer